ADVANCES IN MASLD : A COMPREHENSIVE GUIDE FOR PHYSICIANS

A Comprehensive Guide for Physicians addresses the growing global burden of metabolic dysfunction-associated steatotic liver disease (MASLD), a condition closely linked to obesity, diabetes, and metabolic syndrome. Designed for everyday clinical use, this evidence-based guide covers the full spectrum of MASLD—from its historical evolution and pathophysiology to diagnosis, treatment, and long-term management—integrating the latest guidelines and therapies, including emerging agents like resmetirom and GLP-1 agonists. It provides practical tools such as non-invasive diagnostics (FIB-4, elastography, MRI-PDFF), risk stratification algorithms, and detailed approaches for special populations including children, pregnant women, and those with cirrhosis or hepatocellular carcinoma. Emphasizing a multidisciplinary and personalized care model, the book also explores public health strategies, cost-effective screening, and healthcare implications in both Indian and global contexts. •Comprehensive and Clinically Relevant: Covers all key aspects of MAFLD—from historical evolution and pathophysiology to diagnosis, treatment, and long-term management—tailored for everyday clinical practice. •Evidence-Based and Up-to-Date: Integrates the latest guidelines, research, and therapeutic innovations, including emerging pharmacotherapies like resmetirom and GLP-1 agonists. •Diagnostic and Management Tools: Offers detailed guidance on non-invasive diagnostic techniques (e.g., FIB-4, elastography, MRI-PDFF) and practical algorithms for fibrosis staging and patient risk stratification. •Special Population Coverage: Dedicated chapters on MAFLD in children, adolescents, pregnancy, and advanced disease stages including cirrhosis and hepatocellular carcinoma. •Multidisciplinary and Personalized Approach: Highlights the role of endocrinologists, dietitians, primary care providers, and personalized medicine based on genomic profiles. •Public Health Perspective: Includes critical discussion on cost-effective screening strategies, preventive healthcare policy, and future directions with a focus on Indian and global healthcare settings.

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