Biopharmaceutics and Clinical Pharmacokinetics

About the previous editions... "...a welcome and useful addition to the area of biopharmaceutics and pharmacokinetics and should find wide use as a required text in many pharmaceutics and biopharmaceutics courses." -American Journal of Pharmaceutical Education "... contains abundant material that should be mandatory knowledge not only for pharmacy students, but also for any pharmacists interested in the problems of modern pharmacotherapy." -Drug Intelligence and Clinical Pharmacy "... among the standard books for teaching pharmacokinetics with special emphasis on clinical application." About the fourth edition... -Contemporary Pharmacy Practice For a decade and a half. Biopharmaceutics and Clinical Pharmacokinetics has been used in the classrooms around the world as an introductory textbook on biopharmaceutics and pharmacokinetics.. Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions' proven features, introducing significant advances in clinical pharmacokinetics, pharmacokinetic design of drugs and dosage forms, and model-independent analyses. Still usable without prior knowledge of calculus or kinetics, this successfully implemented work- book maintains a carefully graduated "building block" presentation, incorporating sample problems and exercises throughout for a thorough understanding of the material. Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that system- atically develops and interrelates all subject matter... introduces basic theory and fields of application ... emphasizes model-independent pharmacokinetic analyses. presents biopharmaceutical aspects of product design and evaluation offers a unique approach to teaching dosage regimen design and individualization... and considers structural modification of drug molecules for problems associated with pharmacokinetics. As a comprehensive coverage of the basic principles and the recent achievements in the field, no other textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, and medicine, or for scientists who desire a simple but thorough introduction to theory and application. About the author... ROBERT E. NOTARI is Professor and Chairman in the Division of Pharmaceutics and Pharmaceutical Chemistry at The Ohio State University, Columbus, Ohio, where he has been affiliated since 1964. He has lectured extensively in the United States and Europe, and was a Visiting Professor in Biopharmaceutics and Pharmacokinetics at the University of Aston, Birmingham, England in 1974- 1975. Dr. Notari serves on the editorial board of the Journal of Pharmaceutical Sciences, and has published numerous papers in the fields of chemical kinetics and pharmacokinetics. A Fellow of the Academy of Pharmaceutical Sciences, he has received the Miriam R. Balshone Award for Distinguished Teaching, and coauthored the 1983 Outstanding Research Paper awarded by the Pharmaceutical Research Discussion Group. He received the B.S. (1957) and M.S. (1959) degrees from the Philadelphia College of Pharmacy and Science, and the Ph.D. (1964) degree from the University of Florida.

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