Contemporary Understanding and Management of Cerebral Vasospasm: A Practical Guide

Salient Features A Practical Guide Written by clinicians for clinicians Provides real-world information based on current understanding of the disorder Theon molecular mechanisms outlines exciting and promising new molecules Appendix provides clinical protocols for Subarachnoid Hemorrhage and Vasospasm along with abbreviations Useful in optimiing treatment options across the world Meant for practitioners and for all those involved in the care of Subarachnoid Hemorrhage patients Table of Content The History of Cerebral Vasospasm Definitions and Epidemiology of Vasospasm Recent Topics and Advances in the Molecular Mechanisms Contributing to Cerebral Vasospasm in Subarachnoid Hemorrhage Endothelin- Neuroinflammation and Host Defense Antioxidants and Scavengers of Free Radicals Tenascin-C and Platelet-Derived Growth Factor Inhibition of HMG-CoA Reductase Vasodilators Antiepileptic Drugs The Pathophysiology and Pathology of Cerebral Vasospasm Following Subarachnoid Hemorrhage Anatomic Considerations Morphological Alterations in Cerebral Arteries after Subarachnoid Hemorrhage Pathophysiology of Vasospasm Imaging of Vasospasm: The Role of Magnetic Resonance Imaging in Subarachnoid Hemorrhage-Related Vasospasm Pathophysiology Techniques and Sequences Magnetic Resonance Perfusion Imaging Limitations of Magnetic Resonance Imaging Hyperacute Magnetic Resonance Imaging Protocol Role of Magnetic Resonance Imaging in Patients with Subarachnoid Hemorrhage Perfusion Imaging Vessel Wall Imaging Imaging of Vasospasm: CT, CTA and CTP Correlated with Digital Subtracted Angiography in Cerebral Vasospasm Use of CT, Contrast CT and CTA as Noninvasive Techniques along with TCD and DSA to Identify Probability, Extent and Severity of Vasospasm Technical Features and Scan Acquisition Image Interpretation of Computed Tomography Angiography in Vasospasm Accuracy of Computed Tomography Angiography for Identification and Stratification of Cerebral Vasospasm Computed Tomography Perfusion in Cerebral Vasospasm Limitations, Pitfalls and Problems Imaging of Vasospasm: Transcranial Doppler Ultrasound Imaging: Detecting Intracerebral Arterial Vasospasm Subarachnoid Hemorrhage and Vasospasm Detection Technique Doppler Ultrasound Physics Biosafety Doppler Evaluation of Vasospasm Other Applications of Transcranial Doppler Imaging Contemporary Understanding and Management of Cerebral Vasospasm: A Practical Guide Medical Management of Vasospasm Defining the Problem Monitoring and Triggers Triggers for Intervention Hemodynamic Augmentation Calcium Channel Blockers Magnesium Endothelin Receptor Antagonists Statins Nitric Oxide Fever Control Hyponatremia Adrenal Insufficiency Electroencephalogram Monitoring of Vasospasm Cellular Basis of Electroencephalogram Activity Modifications of Brain Metabolism and Electroencephalogram Activity Secondary to Ischemia Electroencephalogram Studies in Patients with Aneurysmal Subarachnoid Hemorrhage Continuous Electroencephalogram Monitoring for Ischemia Detection Quantitative Electroencephalogram Analysis with the Fast Fourier Transform Artifacts and the use of Intracortical Electroencephalogram Other Confounding Factors and the Need for Multimodality Monitoring Continuous Electroencephalogram for the Monitoring of Treatment Future Developments Anesthesia for Neurointerventional Surgery Anesthetic Management Radiation Protection Practical Microsurgical and Endovascular Treatment of Vasospasm Pathogenesis of Cerebral Vasospasm Medical Prevention and Treatment of Cerebral Vasospasm Special Populations A Pediatric Subarachnoid Hemorrhage B Sickle Cell Disease Appendix: Clinical Protocols Subarachnoid Hemorrhage Protocol Vasospasm Protocol Abbreviations Index

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