Early Clinical Exposure: A Case Based Approach in Clinical Biochemistry, 2/E for MBBS 1st Year Students | 86 Case Studies as per NMC-CBME Curriculum with Question-Answer Format: 1

Early Clinical Exposure: A Case Based Approach in Clinical Biochemistry, 2nd Edition is fully aligned with the Early Clinical Exposure (ECE) guidelines of the 2024 Competency-Based Medical Education (CBME) curriculum mandated by the National Medical Commission (NMC). Rather than a conventional textbook, it is built as 86 short, disease-focused clinical case studies, each followed by a structured question-and-answer set covering diagnosis, biochemical basis, clinical features, investigations, and management. Cases are organized by biochemical theme across sections on Carbohydrates, Lipids, Proteins and Amino Acids, Nucleotides, Vitamins, and Minerals, opening with a COVID-19 case and spanning conditions from G6PD deficiency and diabetic ketoacidosis to phenylketonuria, gout, vitamin deficiencies, and Wilson's disease. Each case is supported by curated illustrations and labeled biochemical-pathway figures that connect the clinical presentation to the underlying biochemistry. Who This Book Is For: First-Year (First Prof) MBBS Students: built to satisfy the mandatory Early Clinical Exposure component of the NMC's CBME curriculum for Biochemistry. MBBS Students (general): the case-based question-answer format supports exam readiness and conceptual clarity beyond the first professional year alone. Why This Book Helps: Fulfils a mandatory curriculum requirement: directly aligned with the NMC's 2024 CBME Early Clinical Exposure guidelines for Biochemistry. Turns biochemistry into clinical reasoning: each case opens with a real clinical vignette before working back to the biochemical mechanism, rather than starting from abstract pathway diagrams. Provides balanced curriculum coverage: case distribution spans Carbohydrates, Lipids, Proteins/Amino Acids, Nucleotides, Vitamins, and Minerals for comprehensive coverage. Aids visual retention: curated illustrations and labeled pathway figures reinforce the clinico-biochemical correlation for each case. Key Features: 86 individual clinical case studies, each in a structured question-and-answer format Organized into 6 biochemical sections: Carbohydrates, Lipids, Proteins and Amino Acids, Nucleotides, Vitamins, and Minerals Covers classic inherited and acquired disorders including G6PD deficiency, galactosemia, phenylketonuria, alkaptonuria, gout, Lesch-Nyhan syndrome, and Wilson's disease Includes labeled biochemical-pathway figures (e.g. pentose phosphate pathway, glutathione redox cycle) tied directly to each case Authored by Anita Chalak, Priti Puppalwar, and Yogesh Pawade — Biochemistry professors with combined CBME/FAIMER medical-education training

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