Recent Advances in Hematology-5

Recent Advances in Hematology-5 is the fifth volume of Jaypee's Recent Advances in Hematology series, a multi-author update in which experts from major centres across India review where practice and evidence currently stand in laboratory and clinical hematology. This volume assembles 41 state-of-the-art articles, each written to critically examine the current literature on one focused topic and to give the reader an up-to-date position plus direction for further reading and discussion. The approach is deliberately multidisciplinary, spanning hematopathology, clinical hematology, hemato-oncology, coagulation and transfusion medicine. Topics include measurable (minimal) residual disease in acute myeloid leukemia and in B-cell and T-cell acute lymphoblastic leukemia, MRD in the CAR-T cell and blinatumomab era, MRD in myeloma, germline predisposition screening in myeloid and lymphoid neoplasms, optical genome mapping and cytogenomics in hematological malignancies, genomic techniques in acute leukemia, monitoring of chronic myeloid leukemia including tyrosine kinase domain mutation assessment, recent advances in Hodgkin lymphoma, juvenile myelomonocytic leukemia, approaches to monocytosis and eosinophilia, microcytic hypochromic anemia not responding to iron, hemoglobin fraction analysis in hemoglobinopathies, updates in antiphospholipid syndrome, heparin-induced and vaccine-induced thrombocytopenia, direct oral anticoagulants, thrombophilia workup, amyloidosis, primary immunodeficiency disorders, new updates in histiocytic disorders, and practical guidance on setting up a diagnostic and molecular hematology laboratory with costing, inventory and quality control. Articles use flow-cytometry plots, peripheral-smear and FISH images, comparative tables and diagnostic algorithms. Who This Book Is For: Pathology and hematology postgraduates and DM trainees (MD, DM, DNB): a structured way to catch up on fast-moving areas such as MRD, molecular cytogenomics and coagulation that standard textbooks lag behind on. Practising hematologists, hematopathologists and transfusion medicine specialists: a consolidated reference for current diagnostic and monitoring practice, with laboratory setup and quality-control guidance. Why This Book Helps: Current position on moving targets: each article distils the recent literature into a usable summary, so time is not lost tracking scattered journal updates. Diagnostic decision support: algorithms and comparative tables guide workup of anemia, monocytosis, eosinophilia, thrombophilia and suspected immunodeficiency. Laboratory practice: dedicated articles on establishing molecular hematology services, costing, inventory and quality control support those building or upgrading a laboratory. Exam-relevant depth: focused coverage of MRD methodology, cytogenomics and transfusion issues matches topics examined in DM and DNB hematology and hematopathology. Key Features: 41 state-of-the-art review articles contributed by experts from major Indian centres. Dedicated coverage of measurable residual disease across AML, B-ALL, T-ALL and myeloma. Articles on optical genome mapping, cytogenomics and genomic techniques in acute leukemia. Coagulation and transfusion topics: antiphospholipid syndrome, HIT and VITT, direct oral anticoagulants, thrombophilia workup. Practical guidance on setting up diagnostic and molecular hematology laboratories with costing, inventory and quality control.

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